Vitamin B12 Cobalamin
Vitamin B12 (cobalamin) plays a role in making DNA. Vitamin B12 also helps maintain healthy nerve cells and red blood cells.
Supporting research & information
Vitamin B12 benefits your mood, energy level, memory, heart, skin, hair, digestion and more. Vitamin B12 is also an essential vitamin for addressing adrenal fatigue, multiple metabolic functions — including enzyme production, DNA synthesis and hormonal balance — and maintaining healthy nervous and cardiovascular systems.
Vitamin B12 benefits the central nervous system in many important ways: It helps maintain the health of nerve cells — including those needed for neurotransmitter signaling — and helps form the protective covering of nerves, called the cell’s myelin sheath. This means that when vitamin B12 levels are low, almost every cognitive function can suffer.
Vitamin B12 — sometimes also called cyanocobalamin, hydroxocobalamin, cobalamin or methylcobalamin — also helps with digestion and heart health, so a deficiency can lead to both digestive disorders and an increased risk for heart disease. It can come in food sources, hydroxocobalimin vitamin B12 injections or as an intramuscular vitamin.
Animal foods are the best food sources of vitamin B12, including organic grass-fed dairy products, cage-free eggs, grass-fed meat, wild-caught fish, organic poultry and organ meats.
Vitamin B12 is part of the Vitamin B complex. It is considered to be a “Painkilling vitamin”. It helps DNA production, cardiovascular support, and energy metabolism. In this post, learn more about Vitamin B12, its functions, causes of deficiencies, as well as foods and other sources so you can better incorporate B12 into your life.
Vitamin B12, also referred to as cobalamin, is a water-soluble vitamin (R).
It contributes to the successful synthesis of DNA, the normal functioning of the nervous system, and the production of energy (R).
The liver is the main site of storage of vitamin B12 in the human body (R). Humans can obtain vitamin B from dietary sources, fortified foods, and supplements (R, R1, R2).
Cyanocobalamin, the most stable and unnatural form of vitamin B12, is most commonly used in supplements and does not have a direct cofactor role in cellular metabolism.
The most biologically significant forms of vitamin B12 are methylcobalamin and coenzyme B12 (5’-deoxy-5’-adenosylcobalamin) (R1 R2).
Vitamin B12 was considered the “Painkilling Vitamin” in some countries as far back as the 1950’s (R).
Vitamin B12 is Essential for the Brain
Methylcobalamin (MeCbl) is the most effectively taken form of vitamin B12 in neuronal organelles (R). Cobalamin may have a role in the prevention of disorders of brain development and mood disorders as well as Alzheimer’s and vascular dementia in the elderly (R).
Supplementation of cobalamin is useful in neuronal regeneration. It also repairs the negative effects of ischemia on neurons (R).
A study on rats with sciatic nerve injuries supports the treatment of peripheral nerve injuries with Cobalamin (R).
B12 also increases regeneration of axons and promotes neuronal repair(R1, R2, R3).
Vitamin B12 Improves Sleeping Patterns
Cobalamin treatment improves sleep-wake rhythm disorders in human subjects (R, R1). It may increase the light sensitivity of circadian rhythms due to decreased melatonin levels (R). It’s not normal to struggle falling asleep and wake up in the morning feeling more tired than when you went to bed. Biohacking Insomnia attacks sleep issues from every angle including limbic system repair, hormone levels, and circadian rhythm retraining.
Vitamin B12 Reduces Depression
In a randomized trial performed on patients with depression and low normal cobalamin levels, cobalamin supplementation improved depressive symptoms (R).